DIFFERENTIAL AFFINITY CHROMATOGRAPHY COUPLED TO MASS SPECTROMETRY: A SUITABLE TOOL TO IDENTIFY COMMON BINDING PROTEINS OF A BROAD-RANGE ANTIMICROBIAL PEPTIDE DERIVED FROM LEUCINOSTATIN

Leucinostatins are antimicrobial peptides with a broad range of activities against infectious agents as well as mammalian cells.The leucinostatin-derivative peptide ZHAWOC_6027 (peptide 6027) was tested in vitro and in vivo for activity against the intracellular apicomplexan parasite Toxoplasma gondii.While highly efficacious in vitro (EC50 = 2 nM)

Cellular metabolomics, which involves targeted and untargeted analyses of metabolites in in vitro systems, plays a BLOND STUDIO 7 pivotal role in system biology.It offers insights into cell phenotypes and provides a means to monitor cellular activities.The power of cellular metabolomics stems from its abilities to quantify and identify metabolites

We outline the ability of zinc phosphate coatings, obtained by chemical conversion, to protect mild BLOND STUDIO 7 steel rebars against localized corrosion, generated by chloride ions in alkaline media.The corrosion resistance of coated steel, in comparison with uncoated rebars and coated and uncoated steel rebars embedded in mortar, were evaluated

The performance of industrial gas turbines is closely tied to the intake air temperature and component performance degradation caused by fouling, erosion, and foreign object damage (FOD).Generally, under hot and Foam Cups humid conditions an increase in the ambient intake air temperature induces a decline in gas turbines performance.With this regar

Omalizumab, a human immunoglobulin (Ig)G1 antibody against IgE, is a therapeutic agent for bronchial asthma.The Global Initiative for Asthma guidelines indicate that the use of omalizumab should be considered as an option in step 5 of treatment for patients with the most severe type of bronchial asthma.In patients with atopic asthma who are at a hi